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Am J Hum Genet 63:13521362

The TRIUMPH-4 trial, focused on adults with obesity and knee osteoarthritis, reported results showing 28.7% mean weight loss at 68 weeks with the 12 mg dose

Our study used a low dose of vitamin C (500 mg) compared to the previous studies investigating liposomal vitamin C formulations (436 g), an amount that is more in line with the generally recommended intake of vitamin C for healthy people, and for groups that are more likely to be at risk of vitamin C inadequacy

597 In addition, bioinformatics analysis shows that Nrf2 is the target of FTO, and FTO impairs Nrf2 mRNA stability through an m6A dependent pathway, revealing the potential function of FTO in PD neurological diseases