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PSC invited comment on the framework until May 1, 2015 and directed its staff to issue a more detailed proposal for additional comment

Combining with Other Ingredients (Retinoids, Acids) Although copper peptides promote repair and collagen synthesis, avoid simultaneous use with highly irritating ingredients: Retinoids (Vitamin A derivatives): Can accelerate exfoliation and may react with copper ions, increasing irritation

Knezevic M, Gojkovic S, Krezic I, Zizek H, Malekinusic D, Vrdoljak B, et al

Native amylin peptides are prone to aggregation and relatively rapid degradation under certain laboratory conditions