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SNP rs5770917 adjacent to the gene encoding CPT1B has been found to be associated with narcolepsy [16]

In addition, TGF- suppresses the activity of ATP synthase in effector memory CD4 + T cells and therefore reduces mitochondria respiratory capacity (Mills et al., 2017), these inhibitory effects on OXPHOS in immune cells may underlie some negative effects of TGF- in immunity