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Studies have demonstrated that daily oral administration of crystalline cyanocobalamin effectively normalizes serum cobalamin levels in deficient patients, although it is unsuitable for rapid supplementation in cases of severe deficiency due to the limited passive absorption

Thus the best-known "function" of B 12 (that which is involved with DNA synthesis, cell division, and anemia) is a facultative function that is mediated by B 12 -conservation of an active form of folate which is needed for efficient DNA production

Additionally, the study explored the effects of these regimens on cognition and depression

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