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In previous studies using an NQO2 knockdown cell line and NQO2 siRNA, the inhibition of NQO2 activity induced the upregulation of antioxidant enzymes, which resulted in increased cellular resistance to oxidants and protected cellular components from oxidation-related damage 56,57,58

A: Water-based paints should be thinned with water, while oil-based paints require a solvent like mineral spirits

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The 10 mg/day arm showed a smaller reduction than the 1 mg group, confirming the absence of a dose-dependent response above the threshold range