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Impact of methylmercury exposure on mitochondrial energetics in AC16 and H9C2 cardiomyocytes

Duckett CS, Perkins ND, Leung K, Agranoff AB, Nabel GJ

Consistent with GSH regulating serine synthesis via post-translational mechanisms, the pharmacologic inhibition of GSH synthesis using buthionine sulfoximine increased liver serine without altering NRF2 or PHGDH expression (22)