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Overlap analysis between the different gene signatures and pathways was performed using the ggVennDiagram module in R

Ras/MAPK (ERK) pathway The most prominent mechanism of ROS-mediated ERK activation starts with the potentiation of EGFR

To account for differences in the duration of vision loss at the time gene therapy was administered, a locally estimated scatterplot smoothing (LOESS) nonparametric local regression model was used to independently assess each patients eyes beginning 12 months after the onset of vision loss, when 92.7% of eyes (139/150) had received treatment

Vitamin C helps boost your immune system and reduce inflammation