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In the absence of mutations in DNA repair-coding genes, FA can also underly a variant of a human inherited bone marrow failure syndrome (IBMFS) caused by mutations in both ALDH2 and ADH5 10, 14

Wree, A

Table 1 Baseline levels of TRP catabolism metabolites as well as neopterin and biopterin in urine in depressed patients and healthy controls

However, technology-based delivery (through the internet, remote communication technologies, or deliverables like DVDs) may improve access to the treatment and may benefit patients reluctant to engage in face-to-face therapy, or unable to conveniently meet with a trained therapist