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Most (83%) who reported a skin reaction after the first dose, did not experience it again after the second dose, according to a study today in JAMA Dermatology

Cancer Prev Res (Phila) 2009;2(7):673682

This rest was associated with increased SRC and mitochondrial mass and decreased mitochondrial membrane potential, fundamental metabolic features associated with memory T cell precursors and superior antitumor activity 6,7,18