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Fever can be absent in 30 to 50% of frail older adults, even in cases of serious infections (Debonera & Simmons, 2021)

doi:10.18071/isz.71.0411 Singh B, Arora S

Moreover, genetic studies show that GRK gene variants are associated with essential hypertension, blood pressure response to antihypertensive medicines, and adverse cardiovascular outcomes of antihypertensive treatment