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miR-7 regulates the EGFR/NF-B/AKT/ERK signaling axis to control the proliferation of intestinal epithelial cells and the secretion of inflammatory cytokines

Lactic acidosis is attributed to mitochondrial DNA gamma polymerase inhibition, resulting in impaired synthesis of mitochondrial enzymes that generate ATP

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Metabolite Interconversion Enzyme was the most represented protein class for ExerVs, specifically Oxidoreductases, which included prostaglandin G_H synthase 1 (PTGS1), glutathione peroxidase 1 (GPX1), glucose-6-phosphate 1-dehydrogenase (G6PD), isocitrate dehydrogenase (mitochondrial, IDH2), malate dehydrogenase (mitochondrial, MDH2), GMP reductase 1 (GMPR), coagulation factor VIII (F8), and polyunsaturated fatty acid lipoxygenase (ALOX12) (Fig