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doi: 10.1016/j.urolonc.2006.12.013 70

In the reported cases, the clinical presentation consisted of recurrent episodes of Reye-like encephalopathy, hypoketotic hypoglycemia, and/or cardiomyopathy

In addition to the PFOS-induced pERK1/2 that is involved in autophagy activation, we revealed the inhibition of pmTOR and pAKT in PFOS-mediated RTC autophagy, which is an effect that can be reversed through l-Carnitine pretreatment (Fig