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Recent studies in pediatric patients have suggested that there might be a 3rd major category of GBM which is distinct from the two GBMs on basis of histone H3F3 gene mutations [16,17]

Measurement of antioxidant enzymes: superoxide dismutase, catalase, and glutathione peroxidase levels The protocols to evaluate the levels of antioxidant enzymes are of key importance to know whether alterations in antioxidant enzymes are directly linked with the diseases incidence and development or just represent secondary symptoms occurring parallel with the diseases, or even consequence of the diseases