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IGFBP-1 and IGFBP-2 are more dynamic, rising with fasting or insulin suppression and falling postprandially [7]

In summary, our study discovers MeCbl as a specific GSDME inhibitor that is promisingly to be developed as an effective drug against cholestatic liver failure, and other GSDME triggered sterile inflammation and/or organ failure

Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses and nitric oxide synthetic pathways

This hyper mutated state leads to an aggressive and rapidly evolving form of CRC (reviewed in ref