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2020 [cited 2025 Mar 14]

We have produced a large-scale computational biology analysis of the SNO-proteome in the cortex of Shank3 mutant mice (a popular model of ASD [171, 282, 283]) and found that among the NO-related molecular alterations, the most prominent change was the activation of the mTOR signaling pathway [171, 176]

Initially, For best results, a series of 4 treatments should be done, 7-10 days apart

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