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Description

Treatment with SAFit2, a potent FKBP51 inhibitor, was found to decrease ubiquitin-positive inclusions, prevent neurodegeneration in the substantia nigra, and improve motor function in NM-SNCAWT (neuromelanin-induced in humanized -synuclein) mouse model [111]

36 Study Protocol Participants were randomly assigned to 1 of 3 groups within fixed blocks of six resulting in eight participants per group: Group one received no supplement