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Vit B12 replacement therapy, typically administered intramuscularly, is the cornerstone of treatment (Marotta and Kesserwani, 2020)

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Cortisol / prolactin & unknown long-term profile: A modest rise in cortisol and prolactin can occur

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This means that an oral bioavailability of 1% can suffice as a top-up once steady state plasma levels are achieved in 4-5 weeks

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