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The high sensitivity (100% for the known carcinogenic and mutagenic NAs tested here) of HepG2 cells supplemented with hamster S9-mix, as compared to PHH and PRH, in principle might make this system a valuable tool for hazard identification and potential follow up of negative/borderline EAT test results to provide further reassurance for the EAT result

34, 35 Vertical smooth pursuit has been reported to be abnormal in 85% of WD patients with neurological features on formal testing with electro-oculography but vision itself remains normal

This treatment involves the careful administration of a small dose of anestheticand sometimes a corticosteroiddirectly into the affected muscle

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