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Certain MC1R variants reduce the capacity for repair to damaged DNA [5], while the process of melanin biosynthesis, particularly of pheomelanin, may itself generate reactive oxygen species and other by-products that may be cytotoxic, genotoxic, or mutagenic causing DNA damage [4, 6]

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"It's not just a wellness or cosmetic product that you use and it's banal and it's harmless it's not." Doctors have been issuing warnings about MT-II for a number of years