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Assessment of polyphenolic content, antioxidant activity, protection against ROS-induced DNA damage and anticancer activity of Vitis vinifera stem extracts

Genetics 77 , 7194 (1974)

45 A longer-term placebo-controlled study found that vitamin B12 deficiency absolute risk was 11.2% greater in the group treated with metformin and the number needed to harm was 8.9 per 4.3 years