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Molecular Nutrition & Food Research, 56(8), 1333-1341

Beyond classic TKIs, the multi-targeted agent anlotinib exerts potent antitumor effects in NSCLC by specifically inducing ferroptosis via the p53/xCT/GPX4 axis (129)

Whereas Afro-Caribbean patients with type 2 diabetes had similar concentrations of total erythrocyte glutathione levels [18] to non-diabetic controls, the concentration of reduced glutathione (GSH) was decreased and oxidized glutathione (GSSG) levels were higher [18] suggesting increased utilization