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In the cytosol/nucleus, SOD1, Prx1/2, GPx1/4 and the Grx/Trx1 systems, supported by abundant GSH, confine ROS and tune thiol switches on enzymes and transcriptional regulators while DNA repair machineries such as OGG1 and the base-excision repair (BER) pathway continuously survey and correct oxidative lesions, together establishing a compartment-aware redox homeostasis that enables signaling yet limits collateral damage (Le Gal et al

These compounds play vital roles in maintaining redox homeostasis, protecting cells from oxidative damage and the toxicity of xenobiotic electrophiles 75,76,77

Trn y l bi vit v glutathione c tc dng g vi da, l thnh phn lm trng da tuyt vi m nh thuc Long Chu gi n bn

SARS-coronavirus open reading frame-3a drives multimodal necrotic cell death