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137 This trial reported statistically significantly greater proportions of patients experiencing improvements in pain in the PPS group (44%) compared to the placebo group (15%) with trends in the same direction for urgency and frequency

Semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2

(29) Female mice were fed a high-fat diet to induce obesity and type 2 diabetes before being treated with semaglutide (10 nmol/kg) or insulin (0.5 U/kg) for up to 28 days

- Not FDA-approved for human use commonly available through research & compounding pharmacies