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general well-being Week 8-12 Optimized benefits plateau

Cortisol Awakening Response (CAR) Measures the cortisol increase just after waking, and helps to assess HPA axis dysfunction and stress resilience through the day

TBX3 played a key role in regulating cellular senescence by repressing p14 ARF expression through interactions with histone deacetylases (HDACs), and by inhibiting p16 INK4a either through suppression of cyclin-dependent kinase activity or by cooperating with the polycomb protein EZH2 to promote its epigenetic silencing [45, 46]