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By contrast, liver-specific Bmal1 KO mice show no significant difference in serum IGF-1 levels compared with WT controls, suggesting the involvement of extrahepatic mechanisms in IGF-1 regulation (54)

other authors are graduate student Justin Wilson and postdoc Ying Song

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[150] In November 2025, the United States President Donald Trump announced a deal with NovoNordisk to lower the costs of Ozempic, including monthly prices of about $245 for injectables and $149 for some oral versions for people on Medicare and Medicaid and for those who use his TrumpRx platform