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The type, timing, and dose of combination therapy depend on further research in the future (266268) ( Figure 5 )

A particular difficulty in assessing the likely biologic functions of isoprostanesseveral of which have been shown to serve as incidental ligands at prostaglandin receptorsis that while high concentrations of individual isoprostanes may be necessary to elicit a response, multiple compounds are formed coincidentally in vivo under conditions of oxidant stress

Astrocytes and Glutamate Homoeostasis in Alzheimer's Disease: A Decrease in Glutamine Synthetase, but Not in Glutamate Transporter1, in the Prefrontal Cortex. ASN Neuro 5: 273282

This method is often used for patients who need injections often or have less muscle mass