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doi: 10.1039/C1RA00934F

& Fearns, R

Strategies to minimize immunogenicity include careful peptide design to maintain similarity to natural sequences, appropriate formulation development, and monitoring for antibody formation during clinical development and post-market surveillance

We assume that small amounts of oxy -TyrBm molecules present in the crystals enabled the activity on HQ within 16 hours that resulted in brown pigmentation 9