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For liquid chromatography, the following solvent gradient of mobile phase A (0.1% FA) and mobile phase B (ACN, 0.1% v/v FA) was applied at a flow rate of 0.4 mL/min: t [min]/B [%]: 0/5

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Cryo-EM maps have been deposited in the Electron Microscopy Data Bank under the following accession codes: for the CagriCTRG s complex, EMD-64557 (raw map), EMD-64558 (receptor-focused refinement map), and EMD-64560 (composite map)

Regular exercise may help attenuate this pathway by enhancing antioxidant capacity and lowering systemic ROS levels, thereby reducing proliferative signaling [64]