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By decreasing production of pro-inflammatory cytokines including IL-6 and TNF-alpha, BPC-157 limits ongoing tissue destruction while simultaneously promoting repair

Important Note on the Evidence Base Important note on the evidence base: The Dihexa research literature is entirely preclinical rodent behavioral models, in vitro hippocampal neuron culture, and mechanistic work characterizing HGF/c-Met-dependent signaling

This is analogous to how 5-Amino-1MQ works in metabolic research-rather than adding a new signal, it removes a brake on an existing one (NNMT inhibition preserves NAD+

It is studied in adults with overweight or obesity (BMI 27 or higher in REDEFINE 1) and in adults with type 2 diabetes (REDEFINE 2 and REIMAGINE 2)