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It is recommended to separate doses of dexpanthenol and succinylcholine by at least 1 hour to decrease the potential for this effect.[1] Sufentanil: (Moderate) Use caution when using dexpanthenol with drugs that decrease gastrointestinal motility, such as opiate agonists, as it may decrease the effectiveness of dexpanthenol.[1] Adverse Reactions / Side Effects There was a case report of respiratory depression following dexpanthenol administration.[1] Two patients experienced vomiting and diarrhea in the days following surgery and dexpanthenol administration.[1] There are minimal case reports of allergic reactions such as pruritus, urticaria, rash (unspecified), tingling, and difficulty breathing

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