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doi: 10.1002/mds.27806 119 MollenhauerB.DaknaM.KruseN.GalaskoD.ForoudT.ZetterbergH.et al

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However, in neurodegenerative conditions, impaired mitochondrial function leads to increased ROS generation and a diminished capacity to neutralize them, resulting in the accumulation of ROS and elevated oxidative stress within brain cells [67,68,87]