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To explore the enhanced dependency on mitochondrial function, we further explored the acute metabolic stress imposed by 5FU treatment

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MOTS-c improved insulin sensitivity and reduced obesity in diet-induced obese mice by activating AMPK [2]

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This indicates that Cu-MOFs exhibit an excellent proportional response behavior to different endogenous H 2 S levels, confirming the applicability of Cu-MOFs as a promising PA developer

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