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Lipid peroxidation and autophagy are closely linked processes, where lipid peroxidation can trigger autophagic responses, and autophagy regulates lipid peroxidation to maintain cellular homeostasis (Fig

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Given this evidence an in-depth understanding of ferroptosis mechanisms involved in the occurrence and development of AD is needed to facilitate timely diagnosis and treatment before major brain damage occurs, improving the survival rate and quality of life of AD patients