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A multicenter randomized clinical trial which evaluates implantation of dexamethasone 350 g or 700 g (Posurdex) versus observation (no therapy) for ME secondary to a variety of retinal disorders (including BRVO) has been reported.117 The preliminary 90-day results of all 315 evaluated patients showed that an improvement in VA of 10 letters or more (in ETDRS) was achieved by a greater proportion of patients treated with dexamethasone 700 g (35%) or 350 g (24%), than untreated patients (13%

The lyophilization procedure was probably responsible for the effect

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After the mixture cooled down, the absorbance value at 500 nm was measured using a microplate reader