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This rare disorder, called pantothenate kinase-associated neurodegeneration (PKAN), is associated with iron accumulation in the brain and characterized by visual and intellectual impairments, dystonia, speech abnormalities, behavioral difficulties, and personality disorders (16-18)

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11 Once it has been synthesized, creatine travels through the bloodstream via sodium- and chloride-dependent creatine transporters to reach its target tissues, like skeletal muscle and brain

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