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Significant inflammation with endotheliitis can lead to disseminated intravascular coagulation (DIC), and thrombosis of small and large vessels with tissue necrosis or infarction

DNA region enriched in hypo-methylation can increase expression of some of the affected genes [10,35,56]

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Long-term COVID 19 sequelae in adolescents: the overlap with orthostatic intolerance and ME/CFS