ionization constants of glutathione Toxicity Glutathione-Binding Metals: A Review of Targets and Mechanisms Oxidation/reduction potential of glutathione |

Consequences of sex differences in Type I IFN responses for the regulation of antiviral immunity Front Immunol

TAMs, through their remarkable metabolic plasticity, modulate iron flux, redox balance, polyunsaturated fatty-acid (PUFA) availability, and glutathione-dependent antioxidant pathways, each of which directly influences ferroptotic vulnerability in neighboring tumor cells

However, after irradiation, GPx1-KO and wild-type mice exhibited almost similar levels of intestinal GPx activity, and this was due to the radiation-induced compensatory upregulation of GPx2 in GPx1-KO mice

Ethics declarations Ethics approval and consent to participate All the animal experimental procedures were in accordance with the guidelines for the Care and Use of Laboratory Animals of Fudan University and approved by the Institutional Animal Care and Use Committee of the School of Pharmacy, Fudan University