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Puerarin, an isoflavone from kudzu root, has also been shown to mitigate pressure-induced heart failure in rats and protect cardiomyocytes from ferroptosis induced by erastin and isoprenaline (232)

Evidence suggests that senescent proximal TECs, when persistently trapped in a state of arrest, exhibit a robust molecular signature characterized by the high expression of VCAM1 [84, 103, 125,126,127]