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The OCTN subclade, comprised of OCTN1 (SLC22A4) and OCTN2, are a distinct subgroup of OCTs that primarily catalyse the uptake of the zwitterionic metabolites ergothioneine 13 and carnitine respectively, but are also capable of transporting cations such as tetraethylammonium (TEA) 14,15 indicating a potential dual transport function 15,16

Virus-induced metabolic disorderobesity Body mass index (BMI) strongly correlates with immune signatures that predict severity of COVID-19 and PASC 752

However, resistance to enzalutamide and apalutamide has been reported in prostate cancer due to a mutation at residue Phe877Leu (213, 224)

[DOI] [PubMed] [Google Scholar] 29.Yang J.M., Li F., Liu Q., Redi M., Wei E.T., Lentsman M., Lee H.S., Choi W., Kim S.J., Yoon K.C