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An integrated analysis of bile acid metabolism in humans with severe obesity

The researchers found that the participants had much lower levels of uric acid during and after the exposure to the cold The study looked at ten healthy people who regularly swim in ice-cold water during the winter

For instance, a study on medium-chain acyl-CoA dehydrogenase deficiency (MCADD) disorder revealed disruptions in phenylalanine, tyrosine, and tryptophan biosynthesis pathways, with potential biomarkers such as PGP (a21:0/PG/F1alpha) and glutathione, demonstrating the importance of metabolomics in promoting our understanding of IEMs [21]

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