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Apoptosis of granulosa cells is higher in patients, which may be associated to decreased serum testosterone levels

For example, CAN often presents with resting tachycardia and orthostatic hypotension, so nonpharmacologic strategies (such as adequate salt intake and physical activities and avoidance of medicine-related hypotension) and pharmacologic strategies (such as midodrine and droxidopa) should be considered to minimize postural symptoms rather than to restore normotension

Increased aggregation and deformability of RBC is also seen in cerebral and myocardial ischemic conditions as well (Bhavsar & Rosenson, 2010

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