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Nano Silver-Induced Toxicity and Associated Mechanisms

The decreased expression of STING suppresses interferon responses, leading to a reduction in CD8 + T and NK cells in the TME, thereby enhancing the effectiveness of anti-PD-1/PD-L1 immunotherapy [123]

More advanced Phase 1 clinical studies deliver further data on the pharmacological effects of the drug candidate in humans, its metabolism, adverse effects associated with dose acceleration, and possibly early effectiveness data

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