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doi: 10.1016/j.intimp.2016.05.015

Greater allergenicity of topical ketoprofen in contact dermatitis confirmed by use

To increase affinity toward CD36, researchers modified the linker region of the VHL-based PROTAC MZ1 by introducing cleavable polar groups (e.g., carboxyl, amino, Boc-protected groups)

Notably, these genetic and epigenetic pathways interact, establishing cancer as a disease influenced by both intrinsic and extrinsic factors rather than isolated genetic events (Ramaiah et al