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If one were to extrapolate from existing human trials: Dose: 0.51 mg per day Route: Sublingual or subcutaneous Duration: Up to 20 days (as used in circadian gene studies) Yet these regimens should not be considered prescriptive or approved protocols

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APE1 was also one of the many non-regulatory proteins involved in cancer survival signaling pathways, and could be used as a therapeutic target in the treatment of multiple types of tumor cells [24]