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Description

Adv Exp Med Biol (2015) 803:191201

The intestinal barrier: a pivotal role in health, inflammation, and cancer

The combination of nave T-cell activation and rapid Gln uptake depends on SLC1A5 (also known as ASCT2), a deficiency of which reduces the differentiation of Th1 cells in vivo , impairs Th1 induction, and attenuates inflammatory T-cell responses (49)