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How exactly vitamin B can worsen acne was recently investigated in a special study (5)

Seitz HK, Bataller R, Cortez-Pinto H, Gao B, Gual A, Lackner C, et al

"Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions." Life Sciences