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Much evidence has accumulated over the past decade suggesting that patients infected with such RNA viruses are under chronic oxidative stress [8] associated with glutathione depletion because oxidative stress, and the associated overproduction of reactive oxygen species, is a hallmark of RNA viruses

Biol Trace Elem Res (2014) 162:3845

1.2.5 Sex-biased differences in T cell exhaustion trajectories and therapeutic responses There are gender differences in the efficacy of immunotherapy and the incidence of autoimmune toxicity observed across different cancer types, for example, men have higher rates of objective response to PD-1/PD-L1 inhibitors in certain tumors, while women tend to experience more severe immune-related adverse events (72)

Int J Sci Eng Res 2(9):15 Reitman S, Frankel S (1957) Determination of glutamate pyruvat transaminase and glutamate oxaloacetate transaminase