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Description

In the modeled PI(3,5)P 2 -bound AtCLCa structure, the inositol head group coordinated by one protomer is at the vicinity of the cytoplasmic H + outlet of the other protomer, and the free C3-phosphate of PI(3,5)P 2 points to the proton glutamate Glu270 (Fig

Acknowledgements The author is grateful to the National Institutes of Health (R35GM142882) for support which enables investigations into halogenation biochemistry in the Agarwal laboratory

Blood and urine sampling and biochemical assays Venous blood samples were collected from each participant at days 0, 1, 3 and 7 after an overnight fast