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Activa la sealizacin vinculada a la renovacin del citoesqueleto y la respuesta angiognica

14 (1): 93102, viii

For instance, AZD1775 (adavosertib) monotherapy has demonstrated antitumor activity in treatment-refractory solid tumors with CCNE1 amplification, with particularly encouraging responses observed in epithelial ovarian cancer in a phase II trial 198 (NCT03253679, ClinicalTrials.gov, 2023)