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Using DNA microarray technology, the researchers found that broccoli sprouts upregulated the expression of several genes involved in both phase I and phase II pathways, and as the synthesis of glutathione, including those associated with cytochrome P450, glutathione metabolism, GSTM1, and NQO1

A single protein, arsenic (+3 oxidation state) methyltransferase (AS3MT), catalyzes both reduction and methylation reactions for As shown in Figure 2

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